Lab Head, Molecular Analytics

Company: Disability Solutions
Location: Cambridge
Posted on: March 27, 2025

Job Description:

Lab Head Molecular Analytics, GSK VaccinesAt GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we have invested in growing our footprint and expanding our R&D space in Cambridge, with a primary focus on additional state-of-the-art lab space. Here, we will bring together talent and expertise, building upon GSK's long history of vaccine development, to create globally leading viral capabilities and innovative vaccines technologies, as we add to our robust portfolio targeting infectious diseases at every stage of life.In the plan to create a new hub for mRNA-based vaccine discovery in Cambridge, we are building new laboratories that will be focused on the development of state-of-the-art methods that will be supporting deep product understanding, process and product development, as well as testing of pre-clinical and clinical samples for new mRNA-based vaccines.The Molecular Analytics group at the US Research and Development Center, GSK Vaccines, is responsible for developing state-of-the-art molecular techniques to characterize and evaluate new vaccine candidates. These expertise's include advanced next-generation sequencing, proteomics, and transcriptomics techniques.We are looking for an initiative-taking scientist and leader with a proven record in utilizing the most up to date genomics/proteomics tools to support the design, development and understanding of best-in-class vaccines, with a particular focus on RNA-based vaccines.Key Responsibilities:

• To provide expertise in the areas of next-generation sequencing, transcriptomics and genomics.
• Develop new analytical techniques to advance the mechanistic understanding of how vaccine candidates work and their critical quality attributes.
• Identify and establish innovative technologies capable of addressing critical questions facing the development of new vaccine entities and platforms.
• Design and develop new assays and technologies to support RNA vaccine design, production, and characterization.
• Provide effective and inspiring leadership with an enterprise mindset, ensuring support to professional development and qualification of staff.
• Ensure the team use cutting-edge technologies and ideas to deliver best preclinical expertise to GSK vaccine projects in discovery, development, and life cycle management.
• Ensure that the objectives of the team are aligned with R&D and business priorities and team activities are designed and delivered according to project needs.
• Takes full accountability of management tasks for the team and meet data integrity and quality expectations.
• Ensures the team delivering assigned activities in the most efficient and resource conscious manner; drives innovation to establish technology in the lab to enhance data quality and resource utilization.
• Possesses strong scientific leadership to enable collaboration with key scientific internal and external stakeholders.
• Participate in IP and regulatory filings and publishes in peer reviewed journals
• Manage a team of 5-10 scientists.
• Supervise PhD students and postdoctoral fellows as needed.
• Accountable for the management monitoring of the laboratory, ensuring that compliance with the GSK Environment, Health and Safety standards are an integral part of the operations and culture.Basic Qualifications:
  • PhD degree in life sciences with at least five years of experience in a related biotechnology field.
  • Five or more years of experience in the fields of next-generation sequencing and bioinformatics, including Illumina sequencing platforms.
  • Five or more years of experience in single-molecule and single-cell techniques, e.g., Oxford Nanopore, Pacific Biosciences, 10Xgenomics etc.
  • Two or more years of experience in managing a team of scientists and forging collaborations in a matrix organization.Preferred Qualifications:
    • Experience in RNA characterization techniques and RNA-based vaccine technology.
    • Strong track-record of scientific publications in peer-reviewed journals.
    • Prior experience in peptide barcoding and sequencing.
    • Fluency in English, spoken and written.
    • Experience in spatial transcriptomics and DNA/RNA barcoding techniques.
    • Background in viral sequence generation and analysis.To be successful in the role, this person must:
      • Demonstrate a detailed fundamental knowledge of an array of different sequencing techniques and technologies.
      • Have practical knowledge in single-molecule and single-cell sequencing technologies and their application to vaccines.
      • Can understand, interpret, and communicate complex scientific data to determine next steps.
      • Be comfortable conversing with opinion leaders regarding highly technical information.
      • Comfortable in managing in a matrix environment.
      • Possess a good balance of creativity and analytical thinking faculties.
      • Display an ability to be productive and successful in an intense work environment as a Team Player.#Vx-Cam#Li-GSKPlease visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Keywords: Disability Solutions, Cambridge , Lab Head, Molecular Analytics, Healthcare , Cambridge, Massachusetts